Basic Info
Model No.: TF2010
Additional Info
Packaging: As Buyer’s Request
Productivity: 100Ton
Brand: Tianfu
Transportation: Ocean,Land,Air,DHL，TNT
Place of Origin: China
Supply Ability: 50Ton
Certificate: ISO
Port: Shanghai port,Qingdao port
Product Description
About the Gossypol Acetate 1, gossypol acetate on the regulation of ovarian hormones has a certain role.
Is mainly for hormone receptor inhibition at early stage, patients can reduce abnormal vaginal estrogen levels, but the serum estradiol, progesterone levels before and after ovulation had no effect.After a period of treatment, the serum hormone level decreased, but the natural recovery after the drug was stopped, does not affect fertility function.
2, the original secondary dysmenorrhea treatment effect
Gossypol acetic acid can inhibit the activity of lysosomal and the synthesis of DNA, which makes arachidonic acid into prostaglandins, this step is blocked, can inhibit the synthesis of prostaglandin and thrombosis.ACTS on the endometrium, can reduce endometrium metabolites prostaglandins and thromboxane in 6 – ketone – PGF1 alpha, TXB2 a significant therapeutic effect.
Compound gossypol acetate film contains vitamin B6, the use of vitamin B6 promote magnesium ions (mg++) through the cell membrane, increase the intracytoplasmic mg++ concentration effect, so as to play to the treatment of primary dysmenorrhea.
3. High concentrations of gossypol, function of enzyme or protein related cell growth, cell apoptosis, but not malignant hyperplasia induced cells
4.Gossypol acetic acid can make endometrial estrogen and progesterone in the dependence of acid phosphatase (ACP), nonspecific lipase (NSE) and alkaline phosphatase (AKP) activity decline, have indirect inhibition of endometrial cells. 5, inhibition of DNA synthesis of endometrial cells
Gossypol acetic acid can inhibit endometrial cells thymine and DNA synthesis, thereby directly inhibit the growth of endometrium atrophy.
High concentrations of gaa enzyme or functional protein can be related to cell growth, cell apoptosis, but not malignant hyperplasia induced cells.
Standard specifications (CERTIFICATION OF ANALYSIS)
| Item | Specification | Method Result | |
| General Analysis | Gossypol acetate 98% | ||
| Assay(Gossypol-acetic acid) Identification Loss on Drying | 98% Identical to R.S. sample ≤5.0% | HPLC HPLC Eur.Ph.6.0[2.8.17] | Conforms Conforms 3.16% |
| Ash | ≤5.0% | Eur.Ph.6.0[2.4.16] 3.52% | |
| Contaminants | |||
| Solvents Residue | Meet Eur.Ph6.0 | Eur.Ph 6.0 Conforms | |
| Pesticides Residue | Meet USP32 | USP32 Conforms | |
| Lead(Pb) | ≤3.0mg/kg | Eur.Ph6.0ICP-MS 2.45 | |
| Arsenic(As) | ≤2.0mg/kg | Eur.Ph6.0ICP-MS 1.29 | |
| Cadmium(Cd) | ≤1.0mg/kg | Eur.Ph6.0ICP-MS 0.68 | |
| Mercury(Hg) | ≤0.1mg/kg | Eur.Ph6.0ICP-MS 0.07 | |
| Microbiological | |||
| Total Plate Count | ≤1000cfu/g | USP30 120 | |
| Yeast &Mold | ≤100cfu/g | USP30 51 | |
| E.Coli. | Negative | USP30 Conforms | |
| Salmonella | Negative | USP30 Conforms  |
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