Product name: Onjisaponin B
Synonym name: Senegin III; Sinegin 3
Catalogue No.: BP1030
Cas No.: 35906-36-6
Formula: C75H112O35
Mol Weight: 1573.69
Botanical Source: Polygala senega and Polygala tenuifolia
Physical Description: Powder
Type of Compound: Triterpenoids
Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle
Storage: Store in a well closed container, protected from air and light. Put into refrigerate or freeze for long term storage.
Whenever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20℃. Generally, these will be useable for up to two weeks.
The product could be supplied from milligrams to grams, up to kilograms
Inquire for bulk scale.
Descriptions:
Onjisaponin B, derived from Radix Polygalae, can enhances autophagy and accelerates the degradation of mutant α-synuclein and huntingtin in PC-12 cells.[1]
Onjisaponin B can reduce β-amyloid production and improve cognitive impairments, indicates that Onjisaponin B is effective against Alzheimer’s disease , providing a new therapeutic agent for further drug discovery.[2]
References:
[1] Wu A G, Wong V K, Xu S W, et al. Int J Mol Sci, 2013, 14(11):22618-41.
[2] Li X, Cui J, Yu Y, et al. Plos One, 2016, 11(3): e0151147.
[3] Dou Z, Hu C M, Wen L, et al. Chinese journal of hospital pharmacy, 2014, 34 (19) : 1676-8.