Product name: Spathulenol
Synonym name:
Catalogue No.: SBP00235
Cas No.: 6750-60-3
Formula: C15H24O
Mol Weight: 220.356
Botanical Source:
Physical Description:
Type of Compound: Sesquiterpenoids
Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle
Storage: Store in a well closed container, protected from air and light. Put into refrigerate or freeze for long term storage.
Whenever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20℃. Generally, these will be useable for up to two weeks.
The product could be supplied from milligrams to grams, up to kilograms
Inquire for bulk scale.
Descriptions:
Spathulenol may be one of the immunomodulatory compounds present in Salvia mirzayanii, it shows the capacity to inhibit proliferation in the lymphocytes and to induce apoptosis in these cells possibly through a caspase-3 independent pathway; treatment of activated lymphocytes with a concentrated fraction containing 62% of spathulenol shows a decrease in the proliferation of lymphocytes with an IC 50 of 85.4 ± 11.08ug/mL. [1]
Spathulenol presents moderate or low cytotoxicity with IC50 higher than 6uM, it is a good candidate to be used in combination chemotherapy of MDR cancer and therefore is worthy for further in vivo studies. [2]
References:
[1] Ziaei A, Ramezani M, Wright L, et al. Phytother Res, 2011, 25(4):557–62.
[2] Vasas A, Molnár J, Hohmann J, et al. Planta Med, 2010, 76(12):1349-1349.
[3] Xu N J, Bai H B, Yan X J, et al. Analysis and Testing Technology, 2006, 25 (1): 90-3.